In humans, a number of antibiotics (streptomycin, penicillin and tetracycline)
have been administered to treat acute leptospirosis.
Penicillin is the drug of choice but other antibiotics are also effective.
·
Penicillin – 6 million units daily intravenously
· Must be given within 4-7 days of onset
Tetracycline for penicillin sensitive patients
A single dose of 25 mg/kg of dihydrostreptomycin has proven to be an
effective procedure.
Non specific treatment – analgesics, antipyretics, antihistaminics
Treatment for complications i.e., dialysis for ARF, mechanical ventilation
for acute respiratory distress syndrome (ARDS).
